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KMID : 1039220200300030270
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Journal of Korean Society of Occupational and Environmental Hygiene
2020 Volume.30 No. 3 p.270 ~ p.279
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Strengthening the Occupational Exposure Limit according to the Results of Epidemiological Studies and Exposure Status to 1-Bromopropane
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Ha Kwon-Chul
Kim Seung-Won
Phee Young-Gyu
Lee Na-Roo
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Abstract
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Objective: The aim of this study was to propose revision of the occupational exposure limit(OEL) for 1?Bromopropane(1-BP) following a review of the appropriateness of the standard in light of increasing epidemiological data and handling risk.
Materials and Methods: The results of toxicity and epidemiologic investigations for 1-BP and agencies’ OELs were compared and reviewed through a literature review. In order to investigate the status of 1-BP handling in South Korea, data from work environment actual condition survey results and work environment measurement results were used.
Results: The toxicity of 1-BP, such as central nervous system(CNS) damage, peripheral neuropathy, hematological adverse effects, and developmental and reproductive toxicity(male and female) has been reported. ACGIH recommends 0.1 ppm as a TLV-TWA value, but the OEL of South Korea stands at 25 ppm, which is 250 times higher than the TLV-TWA. Although 1-BP is a specially managed substance under the Industrial Safety and Health Law, the currently applied OEL cannot be said to be a safe level based on the results of epidemiological studies to date. In a work environment measurement in 2017, the total number of samples was 626, which were derived from 78 industries, and the average concentration was 1.173 ppm(standard deviation 2.88).
Conclusions:To protect the health of workers handling 1-BP, estimated to be 780 in South Korea, it is necessary to strengthen the OEL(TWA) to a level of 0.3 ppm(lower than the 0.34 ppm with known toxic effects), which is believed to be safe as a result of epidemiological investigation. “Skin” notation should be recommended.
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KEYWORD
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1-bromopropane, occupational exposure limit(OEL), work environment measurement
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